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KMID : 1161920160130010043
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Journal of Medicine and Life Science
2016 Volume.13 No. 1 p.43 ~ p.57
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Stevens-Johnson syndrome and toxic epidermal necrolysis: review of concept, etiopathogenesis, diagnosis and management
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Yoon Hyeon-Ji
Kim Jae-Wang
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Abstract
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Stevens-Johnson syndrome/toxic epidermal necrolysis are relatively rare but fatal mucocutaneous drug reactions. It is clinically characterized as a blistering, necrosis, epidermolysis, sloughing and scarring of the skin and mucosa. In Korea, these diseases have been increasingly reported over recent years. Because of higher mortalities and serious complications, early diagnosis and prompt withdrawal of culprit drugs by a clinician is paramount for the adequate management of Stevens-Johnson syndrome/toxic epidermal necrolysis. Herein, we review concept, etiopathogenesis, diagnosis and management of Stevens-Johnson syndrome/toxic epidermal necrolysis.
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KEYWORD
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Stevens-Johnson syndrome, Toxic epidermal necrolysis
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